F9^{tm2.1(F9*R338L*I316T)Tsuka}
Targeted Allele Detail

Summary

• Symbol: F9^{tm2.1(F9*R338L*I316T)Tsuka}
• Name: coagulation factor IX; targeted mutation 2.1, Tsukasa Ohmori
• MGI ID: MGI:7611644
• Synonyms: F9^{tm2.1(hF9_R338L_I316T)Tsuka}
• Gene: F9 Location: ChrX:59044824-59076119 bp, + strand Genetic Position: ChrX, 33.5 cM, cytoband A6-A7
• Alliance: F9^{tm2.1(F9*R338L*I316T)Tsuka} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104881
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The targeting construct inserted the human gene with the mutation CGA to CTA and ATT to ACT mutation resulting in the amino acid substitution of arginine with leucine at position 338 (R338L) and isoleucine with threonine at position 316 (I316T). Flp-mediated recombination removed the selection cassette. (J:104881)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any F9 Mutation: 8 strains or lines available

References

• Original: J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013
• All: 1 reference(s)