Trim65^em1Mji
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim65^em1Mji
• Name: tripartite motif-containing 65; endonuclease-mediated mutation 1, Meixiu Jiang
• MGI ID: MGI:7610649
• Gene: Trim65 Location: Chr11:116012672-116021954 bp, - strand Genetic Position: Chr11, 80.91 cM
• Alliance: Trim65^em1Mji page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a deletion of exons 1-4. (J:345645)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim65 Mutation: 30 strains or lines available

References

• Original: J:345650 Zeng X, et al., LPS inhibits TRIM65 expression in macrophages and C57BL/6J mouse by activating the ERK1/2 signaling pathway. Exp Ther Med. 2023 Apr;25(4):188
• All: 2 reference(s)