Cabcoco1^{tm1b(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Cabcoco1^{tm1b(KOMP)Wtsi}
• Name: ciliary associated calcium binding coiled-coil 1; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:7596106
• Gene: Cabcoco1 Location: Chr10:68266783-68377726 bp, - strand Genetic Position: Chr10, 35.4 cM, cytoband B5.1
• Alliance: Cabcoco1^{tm1b(KOMP)Wtsi} page
• IMPC: Cabcoco1 gene page

Mutation origin

• Mutant Cell Line: EPD0085_5_E04
• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The L1L2_Bact_P cassette was inserted at position 68361159 of Chromosome 10 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 68362062. The critical exon(s) is/are thus flanked by loxP sites. Cre expression without flp expression created a reporter knockout mouse. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cabcoco1 Mutation: 22 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)