Tspo^m1
Spontaneous Allele Detail

Summary

• Symbol: Tspo^m1
• Name: translocator protein; mutation 1
• MGI ID: MGI:7593779
• Synonyms: Tspo^129S6, Tspo^168Pro
• Gene: Tspo Location: Chr15:83447793-83458404 bp, + strand Genetic Position: Chr15, 39.4 cM
• Alliance: Tspo^m1 page

Mutation origin

• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Spontaneous (Not Applicable)
• Mutation: Single point mutation
• Mutation details: This SNP is a spontaneous C-to-G mutation, found in the 129S6 strain, that changes proline codon 168 (CCA) in exon 4 to alanine (GCA) (p.P168A). (J:280448)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tspo Mutation: 14 strains or lines available

References

• Original: J:280448 Klee K, et al., Systemic knockout of Tspo in mice does not affect retinal morphology, function and susceptibility to degeneration. Exp Eye Res. 2019 Nov;188:107816
• All: 1 reference(s)