Cp^em1Jlu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cp^em1Jlu
• Name: ceruloplasmin; endonuclease-mediated mutation 1, Junli Liu
• MGI ID: MGI:7593662
• Synonyms: Cp^flox
• Gene: Cp Location: Chr3:20011218-20063309 bp, + strand Genetic Position: Chr3, 6.1 cM, cytoband D
• Alliance: Cp^em1Jlu page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR-cas9 mediated recombination inserted loxP sites flanking exon 2. (J:345110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cp Mutation: 76 strains or lines available

References

• Original: J:345110 Xie L, et al., Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex. Cell Rep. 2022 Oct 18;41(3):111498
• All: 1 reference(s)