Ecm1^em1Bsun
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ecm1^em1Bsun
• Name: extracellular matrix protein 1; endonuclease-mediated mutation 1, Bing Sun
• MGI ID: MGI:7580778
• Synonyms: ECM1^fl
• Gene: Ecm1 Location: Chr3:95641459-95646880 bp, - strand Genetic Position: Chr3, 40.91 cM
• Alliance: Ecm1^em1Bsun page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exons 6-8 were flanked by loxP sites via CRISPR/Cas9 technology. (J:278032)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ecm1 Mutation: 34 strains or lines available

References

• Original: J:278032 Fan W, et al., ECM1 Prevents Activation of Transforming Growth Factor beta, Hepatic Stellate Cells, and Fibrogenesis in Mice. Gastroenterology. 2019 Jul 27
• All: 2 reference(s)