Egr1^em1Lyd
Endonuclease-mediated Allele Detail

Summary

• Symbol: Egr1^em1Lyd
• Name: early growth response 1; endonuclease-mediated mutation 1, John P Lydon
• MGI ID: MGI:7580744
• Synonyms: Egr1^f
• Gene: Egr1 Location: Chr18:34994260-34998009 bp, + strand Genetic Position: Chr18, 18.76 cM, cytoband C/D
• Alliance: Egr1^em1Lyd page

Mutation origin

• Strain of Origin: C57BL/6NJ

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was flanked by loxP sites via CRISPR/Cas9 technology. (J:344975)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Egr1 Mutation: 19 strains or lines available

References

• Original: J:344975 Maurya VK, et al., A CRISPR/Cas9-engineered mouse carrying a conditional knockout allele for the early growth response-1 transcription factor. Genesis. 2023 Jul;61(3-4):e23515
• All: 1 reference(s)