Ppp6r1^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppp6r1^em1(IMPC)J
• Name: protein phosphatase 6, regulatory subunit 1; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7577005
• Gene: Ppp6r1 Location: Chr7:4634494-4661949 bp, - strand Genetic Position: Chr7, 2.68 cM
• Alliance: Ppp6r1^em1(IMPC)J page
• IMPC: Ppp6r1 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences: CATAGAACATAATCTGAAGG and CATCCAGCATTAGGCTCAGG. This resulted in a 692 bp deletion of Chr7:4,642,957-4,643,648(GRCm38/mm10) that removes exons ENSMUSE00000415805, ENSMUSE00000415802, and ENSMUSE00000415797. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ppp6r1 Mutation: 36 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)