Crbn^em1(CRBN)Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Crbn^em1(CRBN)Gpt
• Name: cereblon; endonuclease-mediated mutation 1, GemPharmatech
• MGI ID: MGI:7576293
• Synonyms: Crbn^{em1Cin(hCRBN)}
• Gene: Crbn Location: Chr6:106757162-106777038 bp, - strand Genetic Position: Chr6, 49.24 cM, cytoband E2
• Alliance: Crbn^em1(CRBN)Gpt page

Mutation origin

• Strain of Origin: BALB/cJGpt

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting replaced the endogenous extracellular domain coding sequence with the humanized sequence. (J:293217)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crbn Mutation: 34 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)