Lrwd1^tm1Kmcn
Targeted Allele Detail

Summary

• Symbol: Lrwd1^tm1Kmcn
• Name: leucine-rich repeats and WD repeat domain containing 1; targeted mutation 1, Kui Ming Chan
• MGI ID: MGI:7574465
• Synonyms: Lrwd1^neo
• Gene: Lrwd1 Location: Chr5:136151920-136164928 bp, - strand Genetic Position: Chr5, 75.8 cM
• Alliance: Lrwd1^tm1Kmcn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326014
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct introduced an FRT-flanked beta-neomycin resistance cassette with a 3' loxP site into intron 5. An additional loxP site was inserted downstream of exon 7. (J:326014)

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrwd1 Mutation: 36 strains or lines available

References

• Original: J:326014 Kang TZE, et al., Lrwd1 impacts cell proliferation and the silencing of repetitive DNA elements. Genesis. 2022 May;60(4-5):e23475
• All: 1 reference(s)