Btla^em2(BTLA)Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Btla^em2(BTLA)Gpt
• Name: B and T lymphocyte associated; endonuclease-mediated mutation 2, GemPharmatech
• MGI ID: MGI:7572964
• Synonyms: Btla^{em1Cin(hBTLA)}
• Gene: Btla Location: Chr16:45043121-45073258 bp, + strand Genetic Position: Chr16, 29.52 cM
• Alliance: Btla^em2(BTLA)Gpt page

Mutation origin

• Strain of Origin: BALB/c-Pdcd1^{em2(PDCD1)Smoc}/Smoc>

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Btla^em2(BTLA)Gpt expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  BTLA (151888)

  Btla	(MGI:2658978)

• Mutation details: CRISPR-targeting replaced the endogenous extracellular domain coding sequence with the humanized sequence. (J:293217)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Btla Mutation: 30 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)