Rr464^em1Stur
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr464^em1Stur
• Name: regulatory region Rr464; endonuclease-mediated mutation 463, Stephen J Turner
• MGI ID: MGI:7567856
• Synonyms: Ccl5 delta-5, delta-5 kb
• Gene: Rr464 Location: unknown Genetic Position: Chr11, Syntenic
• Alliance: Rr464^em1Stur page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Other
• Mutation details: CRISPR/Cas9 technology deleted the transcriptional enhancers at -5 kb from the Ccl5 transcription start site (2186 bp deletion). (J:342875)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr464 Mutation: 0 strains or lines available

References

• Original: J:342875 Russ BE, et al., Active maintenance of CD8(+) T cell naivety through regulation of global genome architecture. Cell Rep. 2023 Oct 31;42(10):113301
• All: 1 reference(s)