Tg(Slc1a6-EGFP)#aRthsn
Transgene Detail

Summary

• Symbol: Tg(Slc1a6-EGFP)#aRthsn
• Name: transgene insertion #a, David Rothstein
• MGI ID: MGI:7564210
• Transgene: Tg(Slc1a6-EGFP)#aRthsn Location: unknown
• Alliance: Tg(Slc1a6-EGFP)#aRthsn page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Tg(Slc1a6-EGFP)#aRthsn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Slc1a6 (MGI:1096331)

• Mutation details: The EAAT4 start codon, in exon 2, was mutated to TTG, and the EGFP cDNA (Clontech) was inserted downstream, after the end of the A-box, within the same exon. Lines 41 and 61 was generated with line 41 exhibiting higher expression levels. Line #a represents the unspecified line used at the Crick Institute. (J:270969)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:270969 Gincel D, et al., Analysis of cerebellar Purkinje cells using EAAT4 glutamate transporter promoter reporter in mice generated via bacterial artificial chromosome-mediated transgenesis. Exp Neurol. 2007 Jan;203(1):205-12
• All: 3 reference(s)