Ackr3^tm1.1Stum
Targeted Allele Detail

Summary

• Symbol: Ackr3^tm1.1Stum
• Name: atypical chemokine receptor 3; targeted mutation 1.1, Ralf Stumm
• MGI ID: MGI:7562044
• Synonyms: HA-ACKR3, HA-Cxcr7
• Gene: Ackr3 Location: Chr1:90131702-90143446 bp, + strand Genetic Position: Chr1, 45.28 cM
• Alliance: Ackr3^tm1.1Stum page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:275611
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Epitope tag)
• Mutation: Insertion
• Mutation details: Sequence coding for an HA tag was inserted immediately downstream of the ATG start codon in exon 2 and a loxP site flanked neomycin resistance gene cassette was inserted into intron 1. The neo cassette was removed through subsequent Cre-mediated recombination. (J:275611)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ackr3 Mutation: 34 strains or lines available

References

• Original: J:275611 Saaber F, et al., ACKR3 Regulation of Neuronal Migration Requires ACKR3 Phosphorylation, but Not beta-Arrestin. Cell Rep. 2019 Feb 5;26(6):1473-1488.e9
• All: 5 reference(s)