Cdc7^tm2.1Hmas
Targeted Allele Detail

Summary

• Symbol: Cdc7^tm2.1Hmas
• Name: cell division cycle 7; targeted mutation 2.1, Hisao Masai
• MGI ID: MGI:7548549
• Synonyms: Cdc7^Fl
• Gene: Cdc7 Location: Chr5:107112201-107132298 bp, + strand Genetic Position: Chr5, 51.43 cM, cytoband E
• Alliance: Cdc7^tm2.1Hmas page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:342120
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting vector PG00062_Z_1_D0 (obtained from the International Mouse Phenotyping Consortium) floxed exons 3 and 4. FLP-mediated recombination removed the FRT-flanked lacZ reporter and selection cassettes. (J:342120)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdc7 Mutation: 33 strains or lines available

References

• Original: J:342120 Hori K, et al., Cdc7 kinase is required for postnatal brain development. Genes Cells. 2023 Oct;28(10):679-693
• All: 1 reference(s)