Nt5e^tm1.1Nsni
Targeted Allele Detail

Summary

• Symbol: Nt5e^tm1.1Nsni
• Name: 5' nucleotidase, ecto; targeted mutation 1.1, Natasha Snider
• MGI ID: MGI:7547172
• Synonyms: CD73^fl
• Gene: Nt5e Location: Chr9:88209662-88254142 bp, + strand Genetic Position: Chr9, 47.24 cM, cytoband E3.2
• Alliance: Nt5e^tm1.1Nsni page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:340331
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 2. Flp-mediated recombination removed the selection cassette. (J:340331)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nt5e Mutation: 31 strains or lines available

References

• Original: J:340331 Alcedo KP, et al., CD73 Maintains Hepatocyte Metabolic Integrity and Mouse Liver Homeostasis in a Sex-Dependent Manner. Cell Mol Gastroenterol Hepatol. 2021;12(1):141-157
• All: 1 reference(s)