Sh2b1^em5Ccsu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sh2b1^em5Ccsu
• Name: SH2B adaptor protein 1; endonuclease-mediated mutation 5, Christin Carter-Su
• MGI ID: MGI:7547155
• Synonyms: Sh2b1betagamma^fl
• Gene: Sh2b1 Location: Chr7:126066166-126074596 bp, - strand Genetic Position: Chr7, 69.06 cM
• Alliance: Sh2b1^em5Ccsu page

Mutation origin

• Strain of Origin: (C57BL/6J x SJL)F2

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 9. (J:340334)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sh2b1 Mutation: 48 strains or lines available

References

• Original: J:340334 Argetsinger LS, et al., Role of the Beta and Gamma Isoforms of the Adapter Protein SH2B1 in Regulating Energy Balance. Endocrinology. 2023 Mar 13;164(5)
• All: 1 reference(s)