Gfral^em3Rsy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gfral^em3Rsy
• Name: GDNF family receptor alpha like; endonuclease-mediated mutation 3, Randy J Seeley
• MGI ID: MGI:7546992
• Gene: Gfral Location: Chr9:76071389-76120939 bp, - strand Genetic Position: Chr9, 42.48 cM
• Alliance: Gfral^em3Rsy page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 through 5. (J:335443)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gfral Mutation: 33 strains or lines available

References

• Original: J:335443 Frikke-Schmidt H, et al., GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice. Mol Metab. 2019 Mar;21:13-21
• All: 3 reference(s)