Lsr^tm1.1Ygng
Targeted Allele Detail

Summary

• Symbol: Lsr^tm1.1Ygng
• Name: lipolysis stimulated lipoprotein receptor; targeted mutation 1.1, Yongfeng Gong
• MGI ID: MGI:7546789
• Synonyms: Lsr^loxP
• Gene: Lsr Location: Chr7:30657195-30672889 bp, - strand Genetic Position: Chr7, 19.27 cM, cytoband A3
• Alliance: Lsr^tm1.1Ygng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:342102
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a self-deletion anchor-flanked neomycin resistance cassette and two loxP site flanking exons 1 through 2. The selection cassette was successfully excised. (J:342102)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lsr Mutation: 32 strains or lines available

References

• Original: J:342102 An Y, et al., LSR targets YAP to modulate intestinal Paneth cell differentiation. Cell Rep. 2023 Sep 26;42(9):113118
• All: 2 reference(s)