Mir375^em1Seth
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir375^em1Seth
• Name: microRNA 375; endonuclease-mediated mutation 1, Praveen Sethupathy
• MGI ID: MGI:7544986
• Synonyms: miR-375 knockout
• Gene: Mir375 Location: Chr1:74939817-74939880 bp, - strand Genetic Position: Chr1, 38.54 cM
• Alliance: Mir375^em1Seth page

Mutation origin

• Strain of Origin: FVB/N X B6(Cg)-Tyr^c-2J/J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The mouse miR-375 gene was deleted using the CRISPR/Cas9 system with a guide RNA (gRNA) targeting the 946965 bp region of the Mir375 gene. (J:342036)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir375 Mutation: 1 strain or line available

References

• Original: J:342036 Hung YH, et al., Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model. BMC Genomics. 2023 Oct 26;24(1):641
• All: 1 reference(s)