Pax7^em1Mru
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pax7^em1Mru
• Name: paired box 7; endonuclease-mediated mutation 1, Michael Rudnicki
• MGI ID: MGI:7544929
• Synonyms: Pax7^KR
• Gene: Pax7 Location: Chr4:139464373-139560839 bp, - strand Genetic Position: Chr4, 70.83 cM
• Alliance: Pax7^em1Mru page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• The Pax7 gene was modified with K193R mutation, generated using CRISPR-Cas9 gene editing. (J:342004)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax7 Mutation: 37 strains or lines available

References

• Original: J:342004 Sincennes MC, et al., Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice. Nat Commun. 2021 May 31;12(1):3253
• All: 1 reference(s)