Dux^tm1.1Kyba
Targeted Allele Detail

Summary

• Symbol: Dux^tm1.1Kyba
• Name: double homeobox; targeted mutation 1.1, Michael Kyba
• MGI ID: MGI:7541342
• Synonyms: Dux^1UnitFL
• Gene: Dux Location: unknown Genetic Position: Chr10, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:341587
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The repeat array was replaced with a loxP site, single copy of one 5 KB unit of the array, FRT-flanked neo cassette and loxP site via homologous recombination. Flp mediated recombination removed the neo cassette. (J:341587)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dux Mutation: 2 strains or lines available

References

• Original: J:341587 Bosnakovski D, et al., Dux facilitates post-implantation development, but is not essential for zygotic genome activation. Biol Reprod. 2021 Jan 4;104(1):83-93
• All: 1 reference(s)