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Prdm16tm1.1Bjo
Targeted Allele Detail
Summary
Symbol: Prdm16tm1.1Bjo
Name: PR domain containing 16; targeted mutation 1.1, Bryan C Bjork
MGI ID: MGI:7541323
Synonyms: Prdm16cGTinv
Gene: Prdm16  Location: Chr4:154400582-154721330 bp, - strand  Genetic Position: Chr4, 83.96 cM, cytoband E2
Alliance: Prdm16tm1.1Bjo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:242985
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsThe conditional gene trap vector FlipROSABgeo* was inserted into intro 2 via homologous recombination. The vector consists of a splice acceptor site, Bgeo* cassette and poly A tail and is flanked by FRT, F3, loxP and lox5171 sites oriented to allow for inversion of the vector. Flp mediated recombination inverted the gene trap vector restoring expression of Prdm16 and preventing expression of the Bgeo reporter. (J:242985)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prdm16 Mutation:  71 strains or lines available
References
Original:  J:242985 Strassman A, et al., Generation of a multipurpose Prdm16 mouse allele by targeted gene trapping. Dis Model Mech. 2017 Jul 01;10(7):909-922
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory