Prdm16^tm1Bjo
Targeted Allele Detail

Summary

• Symbol: Prdm16^tm1Bjo
• Name: PR domain containing 16; targeted mutation 1, Bryan C Bjork
• MGI ID: MGI:7541322
• Synonyms: Prdm16^cGT
• Gene: Prdm16 Location: Chr4:154400582-154721330 bp, - strand Genetic Position: Chr4, 83.96 cM, cytoband E2
• Alliance: Prdm16^tm1Bjo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:242985
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The conditional gene trap vector FlipROSABgeo* was inserted into intro 2 via homologous recombination. The vector consists of a splice acceptor site, Bgeo* cassette and poly A tail and is flanked by FRT, F3, loxP and lox5171 sites oriented to allow for inversion of the vector. (J:242985)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdm16 Mutation: 73 strains or lines available

References

• Original: J:242985 Strassman A, et al., Generation of a multipurpose Prdm16 mouse allele by targeted gene trapping. Dis Model Mech. 2017 Jul 01;10(7):909-922
• All: 3 reference(s)