Tg(Rho-VEGFA)029Rkcz
Transgene Detail

Summary

• Symbol: Tg(Rho-VEGFA)029Rkcz
• Name: transgene insertion 029, Elizabeth Piroska Rakoczy
• MGI ID: MGI:7539685
• Synonyms: KIMBA, trVEGF029
• Transgene: Tg(Rho-VEGFA)029Rkcz Location: unknown
• Alliance: Tg(Rho-VEGFA)029Rkcz page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Rho-VEGFA)029Rkcz expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  VEGFA (7422)

  Vegfa

  (MGI:103178)

• Tg(Rho-VEGFA)029Rkcz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Rho (MGI:97914)

• Mutation details: A human VEGF 165 isoform cDNA is expressed under the control of a truncated mouse rhodopsin promoter. Lines 029, 050, 056, and 094 were generated and show phenotype, and line 029 was studied further and distributed. Line 029 is also known as "Kimba". (J:128552)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:128552 Lai CM, et al., Generation of transgenic mice with mild and severe retinal neovascularisation. Br J Ophthalmol. 2005 Jul;89(7):911-6
• All: 20 reference(s)