Rr463^em1Blk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr463^em1Blk
• Name: regulatory region Rr463; endonuclease-mediated mutation 1, Brian L Black
• MGI ID: MGI:7539494
• Synonyms: Etv2^Enhdelta
• Gene: Rr463 Location: unknown Genetic Position: Chr7, Syntenic
• Alliance: Rr463^em1Blk page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intragenic deletion
• CRISPR-targeting removed the 1.4 kb Etv2 enhancer (chr7:31,423,347-31,425,058; mm9). (J:326086)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr463 Mutation: 0 strains or lines available

References

• Original: J:326086 Sinha T, et al., Differential Etv2 threshold requirement for endothelial and erythropoietic development. Cell Rep. 2022 May 31;39(9):110881
• All: 1 reference(s)