Ilf3^em2Shna
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ilf3^em2Shna
• Name: interleukin enhancer binding factor 3; endonuclease-mediated mutation 2, Shinichi Nakagawa
• MGI ID: MGI:7539163
• Synonyms: Ilf3^deltaPrLD
• Gene: Ilf3 Location: Chr9:21279167-21316657 bp, + strand Genetic Position: Chr9, 7.78 cM, cytoband A4-A5
• Alliance: Ilf3^em2Shna page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting of exon 20 introduced the substitution of C to T to produce a protein lacking the prion-like domain of NFAR2. (J:337564)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ilf3 Mutation: 78 strains or lines available

References

• Original: J:337564 Yamashita A, et al., ILF3 prion-like domain regulates gene expression and fear memory under chronic stress. iScience. 2023 Mar 17;26(3):106229
• All: 1 reference(s)