Cabin1^tm1.1Pada
Targeted Allele Detail

Summary

• Symbol: Cabin1^tm1.1Pada
• Name: calcineurin binding protein 1; targeted mutation 1.1, Peter D Adams
• MGI ID: MGI:7537325
• Synonyms: Cabin1 fl
• Gene: Cabin1 Location: Chr10:75481946-75600175 bp, - strand Genetic Position: Chr10, 38.56 cM
• Alliance: Cabin1^tm1.1Pada page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 6 of the Cabin1 gene is floxed. Flp-mediated recombination removed the selection marker. After Cre-mediated recombination. Deletion of exon 6 will result in the loss of function of the Cabin1 gene by generating a frameshift from exon 5 to exons 7-12 (premature Stop codon in exon 8). (J:101977)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cabin1 Mutation: 114 strains or lines available

References

• Original: J:330257 Smith R, et al., The H3.3 chaperone Hira complex orchestrates oocyte developmental competence. Development. 2022 Mar 1;149(5):dev200044
• All: 3 reference(s)