Pkd1l1^em1Sjka
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pkd1l1^em1Sjka
• Name: polycystic kidney disease 1 like 1; endonuclease-mediated mutation 1, Saul J Karpen
• MGI ID: MGI:7536905
• Synonyms: Pkd1l1^Fl
• Gene: Pkd1l1 Location: Chr11:8782025-8924365 bp, - strand Genetic Position: Chr11, 5.57 cM, cytoband A2
• Alliance: Pkd1l1^em1Sjka page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted upstream and downstream of Exon 8 of the Pkd1l1 gene using CRISPR technologies. (J:335485)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pkd1l1 Mutation: 157 strains or lines available

References

• Original: J:335485 Hellen DJ, et al., Liver-restricted deletion of the biliary atresia candidate gene Pkd1l1 causes bile duct dysmorphogenesis and ciliopathy. Hepatology. 2023 Apr 1;77(4):1274-1286
• All: 1 reference(s)