Lama5^tm1.1Ksek
Targeted Allele Detail

Summary

• Symbol: Lama5^tm1.1Ksek
• Name: laminin, alpha 5; targeted mutation 1.1, Kiyotoshi Sekiguchi
• MGI ID: MGI:7532628
• Synonyms: Lama5^fl
• Gene: Lama5 Location: Chr2:179818166-179867652 bp, - strand Genetic Position: Chr2, 102.7 cM
• Alliance: Lama5^tm1.1Ksek page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:303080
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site, an FRT site, a neomycin resistance gene cassette and a second FRT site were inserted into intron 2 and a second loxP site into intron 3. The neo cassette was removed through subsequent Flp-mediated recombination, leaving exon 3 floxed. (J:303080)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lama5 Mutation: 157 strains or lines available

References

• Original: J:303080 Sato Y, et al., Ventricular-subventricular zone fractones are speckled basement membranes that function as a neural stem cell niche. Mol Biol Cell. 2019 Jan 1;30(1):56-68
• All: 1 reference(s)