Bmal1^tm1Saco
Targeted Allele Detail

Summary

• Symbol: Bmal1^tm1Saco
• Name: basic helix-loop-helix ARNT like 1; targeted mutation 1, Paolo Sassone-Corsi
• MGI ID: MGI:7531719
• Synonyms: Bmal1-stop-FL
• Gene: Bmal1 Location: Chr7:112806672-112913333 bp, + strand Genetic Position: Chr7, 59.17 cM, cytoband F2-F3
• Alliance: Bmal1^tm1Saco page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:290516
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A stop cassette, containing a splice acceptor (SA), a LF2A sequence, mCherry, poly-A tail (PA) and an Frt sequence, is flanked by loxP sites and was inserted between exon 5 and 6 of the Bmal1 gene. (J:290516, J:340991)

Expression

In Mice Carrying this Mutation:

7 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmal1 Mutation: 137 strains or lines available

References

• Original: J:290516 Koronowski KB, et al., Defining the Independence of the Liver Circadian Clock. Cell. 2019 May 30;177(6):1448-1462.e14
• All: 4 reference(s)