Tspan11^tm1Osb
Targeted Allele Detail

Summary

• Symbol: Tspan11^tm1Osb
• Name: tetraspanin 11; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7530607
• Synonyms: Tspan11^{tm1a(EUCOMM)Osb}
• Gene: Tspan11 Location: Chr6:127864585-127930940 bp, + strand Genetic Position: Chr6, 62.56 cM, cytoband F3

Mutation origin

• Germline Transmission: Unknown
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The L1L2_Bact_P cassette was inserted at position 127887742 of Chromosome 6 upstream of the critical exon(s) (Build 37). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter / neomycin phosphotransferase (neoR) gene / SV40 polyA promoter, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 127889379. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. (J:104881)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tspan11 Mutation: 18 strains or lines available

References

• Original: J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013
• All: 1 reference(s)