Stat4^em1Leha
Endonuclease-mediated Allele Detail

Summary

• Symbol: Stat4^em1Leha
• Name: signal transducer and activator of transcription 4; endonuclease-mediated mutation 1, Laurie E Harrington
• MGI ID: MGI:7526058
• Synonyms: STAT4 Flox
• Gene: Stat4 Location: Chr1:52026307-52146348 bp, + strand Genetic Position: Chr1, 26.67 cM
• Alliance: Stat4^em1Leha page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR-targeting produced a floxed allele. (J:340106)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stat4 Mutation: 65 strains or lines available

References

• Original: J:340106 Buzzelli AA, et al., Intrinsic STAT4 Expression Controls Effector CD4 T Cell Migration and Th17 Pathogenicity. J Immunol. 2023 Jun 1;210(11):1667-1676
• All: 1 reference(s)