F8^tm1.2Tsuka
Targeted Allele Detail

Summary

• Symbol: F8^tm1.2Tsuka
• Name: coagulation factor VIII; targeted mutation 1.2, Tsukasa Ohmori
• MGI ID: MGI:7525295
• Synonyms: F8^{tm1.2(EGFP)Tsuka}
• Gene: F8 Location: ChrX:74216321-74426221 bp, - strand Genetic Position: ChrX, 38.17 cM, cytoband A7-B
• Alliance: F8^tm1.2Tsuka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104881
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Hypomorph, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct contains the phage P1 loxP sites, SA, mouse F8 cDNA, Simian Virus (SV40) PolyA, Saccharomyces cerevisiae Frt site, P2A (porcine teschovirus-1 2A peptide), jellyfish EGFP cDNA, and mouse F8 genomic DNA. Flp-mediated recombination removed the selection cassette. cre-mediated recombination removed the floxed segment. (J:104881)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any F8 Mutation: 24 strains or lines available

References

• Original: J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013
• All: 1 reference(s)