Ang^tm1Gfhu
Targeted Allele Detail

Summary

• Symbol: Ang^tm1Gfhu
• Name: angiogenin, ribonuclease, RNase A family, 5; targeted mutation 1, Guo-fu Hu
• MGI ID: MGI:7525280
• Synonyms: Ang1^LoxP
• Gene: Ang Location: Chr14:51328607-51339462 bp, + strand Genetic Position: Chr14, 26.37 cM, cytoband B-C1
• Alliance: Ang^tm1Gfhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:339254
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A pGK-gb2 loxP/FRT-flanked Neomycin cassette was inserted 161 nt upstream from the coding exon 2, and an additional loxP site was inserted 80 nt downstream from the coding exon. (J:339254)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ang Mutation: 15 strains or lines available

References

• Original: J:339254 Yang H, et al., Angiogenin and plexin-B2 axis promotes glioblastoma progression by enhancing invasion, vascular association, proliferation and survival. Br J Cancer. 2022 Aug;127(3):422-435
• All: 3 reference(s)