Tnnt2^em2Bzsh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tnnt2^em2Bzsh
• Name: troponin T2, cardiac; endonuclease-mediated mutation 2, Bin Zhou
• MGI ID: MGI:7522939
• Synonyms: Tnnt2-LSL-mTnG
• Gene: Tnnt2 Location: Chr1:135764092-135779998 bp, + strand Genetic Position: Chr1, 59.32 cM
• Alliance: Tnnt2^em2Bzsh page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: Using the CRISPR/Cas9 technology, the loxP-Stop-loxP-membrane tdTomato-nuclear GFP cDNA was inserted into the 5' UTR of the Tnnt2 gene. (J:339117)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnnt2 Mutation: 50 strains or lines available

References

• Original: J:339117 Liu X, et al., Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle. Nat Commun. 2021 Oct 1;12(1):5784
• All: 1 reference(s)