Ppp1r14a^em1Mhori
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppp1r14a^em1Mhori
• Name: protein phosphatase 1, regulatory inhibitor subunit 14A; endonuclease-mediated mutation 1, Masatoshi Hori
• MGI ID: MGI:7522716
• Gene: Ppp1r14a Location: Chr7:28988732-28992817 bp, + strand Genetic Position: Chr7, 16.94 cM, cytoband A3
• Alliance: Ppp1r14a^em1Mhori page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• With the CRISPR/Cas9, 76 bp DNA fragment of the gene was deleted. (J:271457)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppp1r14a Mutation: 15 strains or lines available

References

• Original: J:271457 Yang Q, et al., The essential role of phospho-T38 CPI-17 in the maintenance of physiological blood pressure using genetically modified mice. FASEB J. 2018 Apr;32(4):2095-2109
• All: 1 reference(s)