Tyro3^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tyro3^em1Cya
• Name: TYRO3 protein tyrosine kinase 3; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7520531
• Synonyms: Tyro3^-/-V2
• Gene: Tyro3 Location: Chr2:119628214-119648585 bp, + strand Genetic Position: Chr2, 59.97 cM, cytoband F
• Alliance: Tyro3^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6NJ-Mertk^em1Cya

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 9413 bp encompassing exons 7 through 18. (J:327995)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tyro3 Mutation: 40 strains or lines available

References

• Original: J:327995 Akalu YT, et al., Tissue-specific modifier alleles determine Mertk loss-of-function traits. Elife. 2022 Aug 15;11:e80530
• All: 2 reference(s)