Rab11fip1^tm1.2Jicn
Targeted Allele Detail

Summary

• Symbol: Rab11fip1^tm1.2Jicn
• Name: RAB11 family interacting protein 1 (class I); targeted mutation 1.2, Jim C Norman
• MGI ID: MGI:7518945
• Gene: Rab11fip1 Location: Chr8:27628801-27664674 bp, - strand Genetic Position: Chr8, 15.91 cM, cytoband A3
• Alliance: Rab11fip1^tm1.2Jicn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:329237
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 2. The neo cassette was removed through subsequent flp-mediated recombination. Cre-mediated recombination removed exon 2. (J:329237)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rab11fip1 Mutation: 38 strains or lines available

References

• Original: J:329237 Rathan-Kumar S, et al., Rab11FIP1-deficient mice develop spontaneous inflammation and show increased susceptibility to colon damage. Am J Physiol Gastrointest Liver Physiol. 2022 Sep 1;323(3):G239-G254
• All: 1 reference(s)