Sema6a^em2Andm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sema6a^em2Andm
• Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; endonuclease-mediated mutation 2, Michael G Anderson
• MGI ID: MGI:7518209
• Gene: Sema6a Location: Chr18:47378321-47504267 bp, - strand Genetic Position: Chr18, 25.08 cM, cytoband C
• Alliance: Sema6a^em2Andm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9-mediated mutation in Sema6a on a pure C57BL/6J background. The mutation is a 20-bp coding sequence deletion in the targeted exon. Predicted to cause frameshift and premature STOP in the next downstream exon. (J:338850)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sema6a Mutation: 84 strains or lines available

References

• Original: J:338850 Meyer KJ, et al., Direct Data Submission of Multiple Allele. MGI Direct Data Submission. 2023
• All: 1 reference(s)