Phb2^em1Jren
Endonuclease-mediated Allele Detail

Summary

• Symbol: Phb2^em1Jren
• Name: prohibitin 2; endonuclease-mediated mutation 1, Jun Ren
• MGI ID: MGI:7516781
• Synonyms: PHB2^flox
• Gene: Phb2 Location: Chr6:124689299-124693913 bp, + strand Genetic Position: Chr6, 59.17 cM
• Alliance: Phb2^em1Jren page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 4 was flanked by loxP sites via CRISRP/Cas9 technology. (J:338856)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Phb2 Mutation: 20 strains or lines available

References

• Original: J:338856 Yang M, et al., PHB2 ameliorates Doxorubicin-induced cardiomyopathy through interaction with NDUFV2 and restoration of mitochondrial complex I function. Redox Biol. 2023 Jul 12;65:102812
• All: 1 reference(s)