Tent5a^em2Adki
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tent5a^em2Adki
• Name: terminal nucleotidyltransferase 5A; endonuclease-mediated mutation 2, Andrzej Dziembowski
• MGI ID: MGI:7514985
• Synonyms: Tent5a^3xFLAG
• Gene: Tent5a Location: Chr9:85202492-85209203 bp, - strand Genetic Position: Chr9, 46.04 cM
• Alliance: Tent5a^em2Adki page

Mutation origin

• Strain of Origin: (C57BL/6JTar x CBA/WTar)F1

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology was used to add a 3xFLAG tag at the C terminus (N447insDYKDHDGDYKDHDIDYKDDDDK). (J:313854)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tent5a Mutation: 19 strains or lines available

References

• Original: J:313854 Gewartowska O, et al., Cytoplasmic polyadenylation by TENT5A is required for proper bone formation. Cell Rep. 2021 Apr 20;35(3):109015
• All: 2 reference(s)