Tg(ACTA2-SLC8A1_i3)1Twmt
Transgene Detail

Summary

• Symbol: Tg(ACTA2-SLC8A1_i3)1Twmt
• Name: transgene insertion 1, Takahiro Iwamoto
• MGI ID: MGI:7514288
• Synonyms: N1.3^Tg, Tg(hSMA-NCX1.3)1
• Transgene: Tg(ACTA2-SLC8A1_i3)1Twmt Location: unknown
• Alliance: Tg(ACTA2-SLC8A1_i3)1Twmt page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTA2-SLC8A1_i3)1Twmt expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  dog	SLC8A1 (475738)

• Tg(ACTA2-SLC8A1_i3)1Twmt expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  dog	ACTA2 (477587)

• The human promoter drives expression of the dog cDNA of isoform 3. (J:94042)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:94042 Iwamoto T, et al., Salt-sensitive hypertension is triggered by Ca(2+) entry via Na(+)/Ca(2+) exchanger type-1 in vascular smooth muscle. Nat Med. 2004 Nov;10(11):1193-9
• All: 2 reference(s)