Cela1^{em1(Hbegf)Bzsh}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cela1^{em1(Hbegf)Bzsh}
• Name: chymotrypsin-like elastase family, member 1; endonuclease-mediated mutation 1, Bin Zhou
• MGI ID: MGI:7514202
• Synonyms: Cela1-DTR
• Gene: Cela1 Location: Chr15:100572303-100585801 bp, - strand Genetic Position: Chr15, 56.38 cM, cytoband F1-F3
• Alliance: Cela1^{em1(Hbegf)Bzsh} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutation: Insertion
• Cela1^{em1(Hbegf)Bzsh} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Hbegf

• Mutation details: Using CRISPR/Cas9, a cDNA encoding DTR was targeted into the translational stop codon of the Cela1 gene, following endogenous Cela by the self-cleaving peptide 2A sequence. (J:338609)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cela1 Mutation: 28 strains or lines available

References

• Original: J:338609 Zhao H, et al., Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas. Cell Discov. 2023 Jan 3;9(1):1
• All: 1 reference(s)