Ptp4a2^tm1Mtr
Targeted Allele Detail

Summary

• Symbol: Ptp4a2^tm1Mtr
• Name: protein tyrosine phosphatase 4a2; targeted mutation 1, Michel L Tremblay
• MGI ID: MGI:7514146
• Synonyms: PRL-2 knockout first
• Gene: Ptp4a2 Location: Chr4:129705012-129743796 bp, + strand Genetic Position: Chr4, 63.38 cM, cytoband D2.3
• Alliance: Ptp4a2^tm1Mtr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:299029
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: LoxP sites flank exon 4 and an frt-flanked lacZ gene and neomycin selection cassette is inserted into intron 3. A knockout first conditional-ready targeting construct designed by EUCOMM was used for targeting. (J:299029)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptp4a2 Mutation: 76 strains or lines available

References

• Original: J:299029 Poulet M, et al., PRL-2 phosphatase is required for vascular morphogenesis and angiogenic signaling. Commun Biol. 2020 Oct 23;3(1):603
• All: 1 reference(s)