Pcbp3em1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Pcbp3em1(IMPC)J |
Name: |
poly(rC) binding protein 3; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:7513904 |
Gene: |
Pcbp3 Location: Chr10:76597691-76797721 bp, - strand Genetic Position: Chr10, 39.72 cM, cytoband B5.1-B5.3
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Alliance: |
Pcbp3em1(IMPC)J page
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IMPC: |
Pcbp3 gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CAGTTCCAGTGATACCCGCA and TGTGTTTTCCACGGGCCATA, which resulted in a 2657 bp deletion beginning at Chromosome 10 position 76,767,806 bp and ending after 76,770,462 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001244493 and ENSMUSE00001226971 (exons 13 and 14) and 2544 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 264 and early truncation 15 amino acids later.
(J:188991)
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Inheritance: |
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Not Specified |
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
1 reference(s) |
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