Lcn8^em1(cre)Xys
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lcn8^em1(cre)Xys
• Name: lipocalin 8; endonuclease-mediated mutation 1, Xiao-yang Sun
• MGI ID: MGI:7512804
• Synonyms: Lcn8-Cre
• Gene: Lcn8 Location: Chr2:25543132-25546229 bp, + strand Genetic Position: Chr2, 17.67 cM, cytoband A3
• Alliance: Lcn8^em1(cre)Xys page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout, Recombinase)
• Mutations: Insertion, Intragenic deletion
• Lcn8^em1(cre)Xys expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lcn8 (MGI:2135945)

• Mutation details: Using CRISPR/Cas9 technology, an NLS-Cre-polyA cassette was inserted into the exon 1 of the Lcn9 gene inframe immediately after the ATG initiation codon. (J:338441)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lcn8 (mouse) Summary of all recombinase alleles driven by Lcn8. Alliance mouse Lcn8 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lcn8 Mutation: 9 strains or lines available

References

• Original: J:338441 Gong QQ, et al., Epididymal initial segment-specific Cre recombinase activity in Lcn8-Cre knock-in mice. Mol Biol Rep. 2021 Aug;48(8):6015-6023
• All: 1 reference(s)