Mirc57^em1Ogu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mirc57^em1Ogu
• Name: microRNA cluster 57, including Gm55686 to Mir669m-1; endonuclease-mediated mutation 1, Atsuo Ogura
• MGI ID: MGI:7511833
• Synonyms: C2MC delta, Sfmbt2 miRNA delta
• Gene: Mirc57 Location: unknown Genetic Position: Chr2, Syntenic

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Mirc57^em1Ogu involves 108 genes/genome features (Gm55686, Gm55687, Mir466m ...) View all
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a 53-kb deletion encompassing the entire miRNA cluster. (J:254511)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc57 Mutation: 0 strains or lines available

References

• Original: J:254511 Inoue K, et al., The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development. Cell Rep. 2017 May 2;19(5):949-956
• All: 4 reference(s)