Maf^em1Eno
Endonuclease-mediated Allele Detail

Summary

• Symbol: Maf^em1Eno
• Name: MAF bZIP transcription factor; endonuclease-mediated mutation 1, Eric N Olsen
• MGI ID: MGI:7511773
• Gene: Maf Location: Chr8:116429992-116433633 bp, - strand Genetic Position: Chr8, 62.61 cM
• Alliance: Maf^em1Eno page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a 458 bp deletion and introduce a preamture stoop codon in exon 1. (J:338268)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Maf Mutation: 27 strains or lines available

References

• Original: J:338268 Dos Santos M, et al., Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution. Nat Commun. 2023 Jul 19;14(1):4333
• All: 1 reference(s)