Mmp17^tm1.1Arro
Targeted Allele Detail

Summary

• Symbol: Mmp17^tm1.1Arro
• Name: matrix metallopeptidase 17; targeted mutation 1.1, Alicia G Arroyo
• MGI ID: MGI:7511769
• Synonyms: MT4-MMP^f
• Gene: Mmp17 Location: Chr5:129661233-129688163 bp, + strand Genetic Position: Chr5, 68.18 cM
• Alliance: Mmp17^tm1.1Arro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:338296
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and FRT flanked pgk-neo cassette were inserted upstream of exon 2 and a loxP site was inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:338296)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mmp17 Mutation: 35 strains or lines available

References

• Original: J:338296 Sahun-Espanol A, et al., p38 MAPK priming boosts VSMC proliferation and arteriogenesis by promoting PGC1alpha-dependent mitochondrial dynamics. Sci Rep. 2022 Apr 8;12(1):5938
• All: 1 reference(s)